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Independiente Medellin vs Santa Fe

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The Independiente Medellin vs Santa Fe game on 21.10.2025 is packed with betting value, and our expert predictions cover key markets such as Over 2.5 goals, BTTS, and total goals. With our in-depth analysis of team form, goal-scoring trends, and past encounters, you’ll have the best insights for making winning bets on this exciting match.
Bet and Win Predictions, H2H Stats and Recent Results.
Betting Tips and Predictions:
| Prediction | Odds | Source |
|---|---|---|
| Independiente Medellin is expected to be the likely winner. | 1.65 | ![]() |
| BTTS: Yes | 1.90 | ![]() |
| U 2.5 | 1.95 | ![]() |
Streak Insights
- Independiente Medellin are unbeaten in 4 straight matches. Double Chance (1X): 1.15.
- Independiente Medellin have won 3 in a row. 1×2 Home: 1.65.
- Independiente Medellin matches have seen Over 2.5 in 5 straight. O2.5: 1.90.
- Both Teams to Score landed in 5 straight Independiente Medellin matches. BTTS Yes: 1.90.
Independiente Medellin

Team Form and Performance Overview:
Independiente Medellin have shown strong consistency, winning 3 matches in their recent 5, proving tough competition! They’ve also drawn 1 games and suffered 1 losses.
All of their last 5 matches have featured both teams on the score sheet. Plenty of attacking play!
Every match in their last 5 games has been a goal fest, with over 2.5 goals in each of them!
Overall, Independiente Medellin have scored 14 goals and conceded 8 goals in their last 5 matches.
| Date | Match Details |
|---|---|
| 17.10.2025 | Independiente Medellin 3 – 1 Fortaleza FC W |
| 13.10.2025 | Once Caldas 1 – 5 Independiente Medellin W |
| 27.09.2025 | Deportes Tolima 2 – 3 Independiente Medellin W |
| 21.09.2025 | Independiente Medellin 2 – 2 Junior D |
| 13.09.2025 | Rionegro Aguilas 2 – 1 Independiente Medellin L |
Santa Fe

Team Form and Performance Overview:
Santa Fe have been solid, picking up 2 wins in their last 5 games. They’ve also drawn 2 games and suffered 1 losses.
Their recent games have been quite even, with 2 matches out of 5 seeing both teams score.
2 matches out of 5 have seen over 2.5 goals, offering a mix of high-scoring and tighter contests.
Overall, Santa Fe have scored 7 goals and conceded 4 goals in their last 5 matches.
| Date | Match Details |
|---|---|
| 18.10.2025 | Chico 0 – 0 Santa Fe D |
| 12.10.2025 | Santa Fe 1 – 3 Llaneros L |
| 28.09.2025 | Santa Fe 3 – 0 La Equidad W |
| 20.09.2025 | Deportivo Pasto 1 – 1 Santa Fe D |
| 14.09.2025 | Santa Fe 2 – 0 Union Magdalena W |
Head-to-Head
H2H Matches between Independiente Medellin and Santa Fe
| 29.06.2025 | Independiente Medellin 1 – 2 Santa Fe |
| 25.06.2025 | Santa Fe 0 – 0 Independiente Medellin |
| 15.04.2025 | Santa Fe 1 – 2 Independiente Medellin |
| 19.10.2024 | Santa Fe 1 – 1 Independiente Medellin |
| 11.02.2024 | Independiente Medellin 1 – 1 Santa Fe |
Standings
| # | Club | MP | W | D | L | GF | GA | GD | PTS | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Junior |
16 | 9 | 4 | 3 | 30 | 19 | 11 | 31 | WWLWD |
| 2 | Bucaramanga |
15 | 9 | 3 | 3 | 26 | 12 | 14 | 30 | WWLWD |
| 3 | Independiente Medellin |
15 | 9 | 3 | 3 | 33 | 21 | 12 | 30 | WWLWD |
| 4 | Atletico Nacional |
16 | 7 | 7 | 2 | 27 | 19 | 8 | 28 | DWDWW |
| 5 | Fortaleza FC |
16 | 7 | 7 | 2 | 21 | 16 | 5 | 28 | LWDWL |
| 6 | Llaneros |
16 | 7 | 4 | 5 | 16 | 14 | 2 | 25 | WWDLL |
| 7 | Deportes Tolima |
15 | 7 | 2 | 6 | 18 | 14 | 4 | 23 | LWLLW |
| 8 | Santa Fe |
15 | 5 | 6 | 4 | 16 | 14 | 2 | 21 | DLWDW |
| 9 | Rionegro Aguilas |
16 | 5 | 6 | 5 | 21 | 22 | -1 | 21 | WDWLW |
| 10 | America de Cali |
16 | 5 | 5 | 6 | 16 | 15 | 1 | 20 | WWLDW |
| 11 | Alianza Petrolera |
16 | 5 | 5 | 6 | 19 | 21 | -2 | 20 | LLDWD |
| 12 | Deportivo Cali |
16 | 5 | 5 | 6 | 20 | 23 | -3 | 20 | LLWLW |
| 13 | Once Caldas |
16 | 5 | 4 | 7 | 18 | 23 | -5 | 19 | LLWWL |
| 14 | Deportivo Pereira |
16 | 4 | 6 | 6 | 17 | 19 | -2 | 18 | LWLDD |
| 15 | Union Magdalena |
16 | 5 | 3 | 8 | 20 | 26 | -6 | 18 | WLWDL |
| 16 | Millonarios |
15 | 5 | 2 | 8 | 18 | 23 | -5 | 17 | LWLWL |
| 17 | Envigado |
16 | 3 | 7 | 6 | 14 | 18 | -4 | 16 | LWLDD |
| 18 | Deportivo Pasto |
16 | 2 | 7 | 7 | 19 | 25 | -6 | 13 | DDDLL |
| 19 | Chico |
16 | 2 | 7 | 7 | 11 | 23 | -12 | 13 | DLDLD |
| 20 | La Equidad |
15 | 2 | 5 | 8 | 9 | 22 | -13 | 11 | LLLLD |
Independiente Medellin vs Santa Fe match | 21.10.2025 Football predictions are easier with our H2H stats and expert betting tips. We provide the best daily match previews and comprehensive analysis for leagues worldwide. Explore bookmaker bonuses and special offers for more value.



















